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TABLE OF CONTENTS
VIII

ABSTRACT
UITTREKSEL
AIM AND OBJECTIVES

X

XI1

CHAPTER 1: PHYSICO- PROPERTIES, FUNCTION AND
USES OF UREA
1.1 Introduction
1.2 The history of urea and moisturisers
1.3 Cosmeceutics and delivery systems
1.3.1 The skin and its permeability
1.3.2 Structural basis for percutaneous absorption pathways
1.3.3 Transcellular vs. intercellular pathways
1.3.4 Skin moisturisers

1.4 Pharmacological action
1.5 Physical and chemical properties
1.6 Stability
1.7 Uses
1.8 Adverse effects
1.9 Precautions and contraindications
1.10 Antimicrobial activity
1.11 Conclusion